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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Adam Eaton | 2015-2021 | .243 | 11 | 142 | 0 | 0 | 0 | 0.00 | 0 |
| Josh Edgin | 2015-2023 | .000 | 0 | 0 | 24 | 10 | 16 | 2.44 | 438 |
| C.J. Edwards | 2016-2024 | .000 | 0 | 0 | 38 | 42 | 185 | 3.31 | 664 |
| Xavier Edwards | 2022-2025 | .288 | 47 | 258 | 0 | 0 | 0 | 0.00 | 0 |
| Zach Eflin | 2018-2025 | .000 | 0 | 0 | 31 | 41 | 0 | 4.46 | 390 |
| Jerad Eickhoff | 2016-2025 | .000 | 0 | 0 | 94 | 76 | 2 | 4.18 | 1268 |
| Scott Elbert | 2016-2016 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Roenis Elias | 2017-2017 | .000 | 0 | 0 | 1 | 1 | 0 | 6.94 | 24 |
| Brian Ellington | 2022-2022 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 1 |
| A.J. Ellis | 2015-2015 | .240 | 6 | 23 | 0 | 0 | 0 | 0.00 | 0 |
| Jim Ellis | 2024-2025 | .000 | 0 | 0 | 10 | 21 | 1 | 4.85 | 214 |
| Jacoby Ellsbury | 2015-2019 | .271 | 30 | 138 | 0 | 0 | 0 | 0.00 | 0 |
| Edwin Encarnacion | 2015-2017 | .233 | 38 | 125 | 0 | 0 | 0 | 0.00 | 0 |
| Max Engelbrekt | 2021-2024 | .000 | 0 | 0 | 16 | 9 | 8 | 3.58 | 290 |
| Tristin English | 2021-2025 | .000 | 0 | 0 | 8 | 4 | 4 | 4.17 | 178 |
| Nathan Eovaldi | 2015-2019 | .000 | 0 | 0 | 13 | 16 | 2 | 4.27 | 259 |
| Phil Ervin | 2020-2021 | .214 | 3 | 9 | 0 | 0 | 0 | 0.00 | 0 |
| Alcides Escobar | 2015-2015 | .244 | 0 | 19 | 0 | 0 | 0 | 0.00 | 0 |
| Yunel Escobar | 2015-2015 | .241 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Thomas Eshelman | 2021-2022 | .000 | 0 | 0 | 4 | 7 | 0 | 4.43 | 97 |
| António Esparza | 2025-2025 | .000 | 0 | 0 | 1 | 0 | 1 | 1.93 | 24 |
| Yonathan Estiwal | 2025-2025 | .277 | 18 | 64 | 0 | 0 | 0 | 0.00 | 0 |
| DeMarcus Evans | 2020-2020 | .000 | 0 | 0 | 0 | 2 | 0 | 0.66 | 29 |
