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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Postseason Career Leaderboard |
|---|---|---|---|---|
| 1 | Aaron Blair# | 36.0 | 2024 | |
| 2 | Jose Urena# | 33.0 | 2025 | |
| 2 | Anthony Molina# | 33.0 | 2024 | |
| 2 | Matt Krook# | 33.0 | 2024 | |
| 5 | Alex Wood# | 32.0 | 2017 | |
| 6 | Kensaku Yamaguchi# | 31.0 | 2024 | |
| 7 | Marcus Stroman# | 30.0 | 2019 | |
| 8 | Zack Greinke | 29.0 | 2016 | |
| 8 | Sonny Gray# | 29.0 | 2017 | |
| 10 | Jose Fernandez# | 28.0 | 2018 | |
| 10 | Jake Arrieta | 28.0 | 2015 | |
| 10 | Zach Petrick# | 28.0 | 2023 | |
| 13 | Jim Bartlett# | 27.0 | 2024 | |
| 13 | Aaron Blair# | 27.0 | 2023 | |
| 15 | Chris Sale# | 26.0 | 2016 | |
| 15 | Alex Reyes# | 26.0 | 2025 | |
| 17 | Madison Bumgarner# | 25.0 | 2015 | |
| 17 | Noah Murdock# | 25.0 | 2025 | |
| 17 | Shelby Miller# | 25.0 | 2024 | |
| 20 | Zach Petrick# | 24.0 | 2024 | |
| 20 | Ben Jordan# | 24.0 | 2025 | |
| 20 | Archie Bradley | 24.0 | 2015 | |
| 23 | Max Scherzer | 23.0 | 2017 | |
| 23 | Noah Syndergaard# | 23.0 | 2020 | |
| 23 | Stephen Strasburg | 23.0 | 2017 | |
| 23 | Marcus Stroman# | 23.0 | 2021 | |
| 23 | Zack Greinke | 23.0 | 2015 | |
| 28 | Matt Krook# | 22.0 | 2023 | |
| 28 | Sandy Koufax# | 22.0 | 2023 | |
| 28 | Jackson Kowar# | 22.0 | 2020 | |
| 28 | Joe Gray# | 22.0 | 2023 | |
| 28 | Grayson Garvin# | 22.0 | 2023 | |
| 28 | Toby Kelly# | 22.0 | 2025 | |
| 28 | Anthony Molina# | 22.0 | 2025 | |
| 28 | Cole Hamels | 22.0 | 2016 | |
| 36 | Chris Sale# | 21.0 | 2025 | |
| 36 | Sandy Koufax# | 21.0 | 2024 | |
| 36 | Cole Hamels | 21.0 | 2015 | |
| 36 | Matt Wisler# | 21.0 | 2017 | |
| 36 | Jerad Eickhoff# | 21.0 | 2019 | |
| 36 | Blake Snell# | 21.0 | 2023 | |
| 36 | Charles King# | 21.0 | 2025 | |
| 36 | Chris Sale# | 21.0 | 2022 | |
| 44 | Ethan Small# | 20.0 | 2025 | |
| 45 | Noah Syndergaard# | 19.0 | 2019 | |
| 45 | Marcus Stroman# | 19.0 | 2015 | |
| 45 | Jake Thompson# | 19.0 | 2019 | |
| 45 | Gerrit Cole | 19.0 | 2015 | |
| 45 | Masahiro Tanaka | 19.0 | 2018 | |
| 45 | Tyler Glasnow# | 19.0 | 2018 | |
| 51 | Jake Arrieta | 18.0 | 2016 | |
| 51 | Aaron Nola# | 18.0 | 2021 | |
| 51 | Javier Medina# | 18.0 | 2023 | |
| 51 | Cole Hamels | 18.0 | 2021 | |
| 51 | Matt Boyd# | 18.0 | 2025 | |
| 51 | William Heflin# | 18.0 | 2025 | |
| 51 | Felix Hernandez | 18.0 | 2016 | |
| 51 | Reggie Lawson# | 18.0 | 2020 | |
| 51 | Sonny Gray# | 18.0 | 2016 | |
| 51 | Cole Irvin# | 18.0 | 2021 | |
| 51 | Noah Murdock# | 18.0 | 2024 | |
| 51 | Robby Stone# | 18.0 | 2023 | |
| 63 | Danny Duffy | 17.0 | 2023 | |
| 63 | Daniel Norris | 17.0 | 2016 | |
| 63 | Matt Wisler# | 17.0 | 2016 | |
| 63 | Julio Urias# | 17.0 | 2025 | |
| 63 | Cal García# | 17.0 | 2025 | |
| 63 | Carlos Rodon# | 17.0 | 2022 | |
| 63 | Matt Wisler# | 17.0 | 2018 | |
| 70 | Sonny Gray# | 16.0 | 2018 | |
| 70 | Hisashi Iwakuma | 16.0 | 2016 | |
| 70 | Chris Sale# | 16.0 | 2017 | |
| 70 | Jose Urena# | 16.0 | 2024 | |
| 70 | Noah Syndergaard# | 16.0 | 2015 | |
| 70 | Jake Thompson# | 16.0 | 2021 | |
| 70 | Garrett Richards | 16.0 | 2016 | |
| 70 | Francisco Liriano | 16.0 | 2015 | |
| 70 | Takahiro Norimoto# | 16.0 | 2021 | |
| 70 | Jerad Eickhoff# | 16.0 | 2024 | |
| 70 | Chris Sale# | 16.0 | 2018 | |
| 70 | Nick Pratto# | 16.0 | 2025 | |
| 70 | Jerad Eickhoff# | 16.0 | 2020 | |
| 70 | Matt Wisler# | 16.0 | 2022 | |
| 70 | Takahiro Norimoto# | 16.0 | 2020 | |
| 85 | Ben Jordan# | 15.0 | 2024 | |
| 85 | Jacob deGrom | 15.0 | 2015 | |
| 85 | Juan Hillman# | 15.0 | 2023 | |
| 85 | Masahiro Tanaka | 15.0 | 2017 | |
| 85 | Evan Scribner | 15.0 | 2021 | |
| 85 | Damien Magnifico# | 15.0 | 2022 | |
| 91 | Jeurys Familia | 14.0 | 2022 | |
| 91 | Brady Singer# | 14.0 | 2023 | |
| 91 | Carlos Martinez | 14.0 | 2018 | |
| 91 | Michael Wacha# | 14.0 | 2023 | |
| 91 | Kolby Allard# | 14.0 | 2025 | |
| 91 | Dan Stevens# | 14.0 | 2023 | |
| 91 | Jackson Kowar# | 14.0 | 2022 | |
| 91 | Takeru Kawakami# | 14.0 | 2023 | |
| 91 | Yu Darvish | 14.0 | 2016 | |
| 91 | Yordano Ventura# | 14.0 | 2025 |
