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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Chris Sale# | 138.2 | 2015-2025 | |
| 2 | Sonny Gray# | 117.1 | 2015-2025 | |
| 3 | Matt Wisler# | 114.1 | 2016-2025 | |
| 4 | Marcus Stroman# | 105.2 | 2015-2025 | |
| 5 | Cole Hamels | 96.1 | 2015-2022 | |
| 6 | Jose Fernandez# | 83.0 | 2015-2025 | |
| 7 | Aaron Blair# | 78.0 | 2020-2025 | |
| 8 | Noah Syndergaard# | 74.2 | 2015-2025 | |
| 9 | Jackson Kowar# | 73.0 | 2019-2025 | |
| 10 | Jerad Eickhoff# | 67.2 | 2016-2025 | |
| 11 | Anthony Molina# | 67.1 | 2022-2025 | |
| 12 | Jose Urena# | 61.2 | 2018-2025 | |
| 13 | Matt Krook# | 61.1 | 2020-2025 | |
| 14 | Zach Petrick# | 59.2 | 2018-2025 | |
| 15 | Masahiro Tanaka | 58.0 | 2015-2024 | |
| 16 | Carlos Martinez | 55.0 | 2015-2023 | |
| 17 | Zack Greinke | 52.2 | 2015-2018 | |
| 18 | Stephen Strasburg | 49.1 | 2015-2021 | |
| 19 | Alex Claudio# | 47.1 | 2015-2025 | |
| 20 | Jake Arrieta | 46.2 | 2015-2021 | |
| 21 | Jordan Walden# | 45.1 | 2015-2025 | |
| 22 | Sandy Koufax# | 44.0 | 1955-2025 | |
| 23 | Noah Murdock# | 43.1 | 2023-2025 | |
| 24 | Shelby Miller# | 43.0 | 2015-2025 | |
| 24 | Alex Wood# | 43.0 | 2015-2025 | |
| 26 | Aaron Nola# | 41.2 | 2015-2025 | |
| 27 | Jake Thompson# | 41.1 | 2018-2025 | |
| 28 | Ben Jordan# | 40.1 | 2021-2025 | |
| 28 | Aaron Slegers# | 40.1 | 2019-2025 | |
| 30 | Kelvin Herrera | 40.0 | 2015-2025 | |
| 31 | Robby Stone# | 39.2 | 2020-2025 | |
| 32 | Alex Reyes# | 37.2 | 2020-2025 | |
| 32 | Kensaku Yamaguchi# | 37.2 | 2023-2025 | |
| 34 | Toby Kelly# | 35.1 | 2022-2025 | |
| 35 | Grayson Garvin# | 35.0 | 2017-2025 | |
| 36 | Justin De Fratus# | 33.0 | 2015-2024 | |
| 37 | Kolby Allard# | 32.1 | 2020-2025 | |
| 37 | Madison Bumgarner# | 32.1 | 2015-2022 | |
| 37 | Takahiro Norimoto# | 32.1 | 2019-2025 | |
| 40 | Carter Capps# | 31.2 | 2015-2025 | |
| 41 | Joe Gray# | 30.2 | 2023-2025 | |
| 41 | Dan Stevens# | 30.2 | 2022-2025 | |
| 43 | Matt Harvey | 30.0 | 2015-2023 | |
| 44 | Yordano Ventura# | 29.1 | 2016-2025 | |
| 45 | Jim Bartlett# | 28.0 | 2023-2025 | |
| 46 | Jacob deGrom | 27.1 | 2015-2022 | |
| 46 | Jeurys Familia | 27.1 | 2015-2025 | |
| 46 | Parker McFadden# | 27.1 | 2021-2025 | |
| 46 | Mike Morin# | 27.1 | 2016-2025 | |
| 50 | Dakota Bacus# | 26.2 | 2019-2025 | |
| 50 | Gerrit Cole | 26.2 | 2015-2025 | |
| 50 | Tyler Glasnow# | 26.2 | 2017-2025 | |
| 50 | Damien Magnifico# | 26.2 | 2016-2025 | |
| 54 | Steven Okert# | 26.1 | 2018-2025 | |
| 54 | Carlos Rodon# | 26.1 | 2018-2025 | |
| 56 | Sean Doolittle | 25.0 | 2015-2019 | |
| 56 | Drew Storen# | 25.0 | 2015-2025 | |
| 58 | Matt Boyd# | 24.2 | 2019-2025 | |
| 59 | Drew Smyly | 24.1 | 2015-2023 | |
| 60 | Archie Bradley | 24.0 | 2015-2018 | |
| 61 | Mike Foltynewicz# | 23.2 | 2015-2025 | |
| 61 | Max Scherzer | 23.2 | 2015-2021 | |
| 63 | Juan Hillman# | 23.1 | 2020-2025 | |
| 63 | Evan Scribner | 23.1 | 2015-2021 | |
| 65 | Mark Melancon | 23.0 | 2015-2023 | |
| 65 | Bryan Price | 23.0 | 2015-2022 | |
| 65 | Jameson Taillon# | 23.0 | 2016-2025 | |
| 68 | Shae Simmons# | 22.2 | 2015-2025 | |
| 69 | C.J. Edwards | 22.1 | 2016-2024 | |
| 70 | Daniel Hudson | 21.2 | 2015-2017 | |
| 70 | Hunter Parsons# | 21.2 | 2022-2025 | |
| 72 | Takeru Kawakami# | 21.0 | 2023-2025 | |
| 72 | Charles King# | 21.0 | 2023-2025 | |
| 72 | Blake Snell# | 21.0 | 2019-2025 | |
| 75 | Daniel Winkler# | 20.2 | 2017-2025 | |
| 76 | Dailyn De Oleo# | 20.1 | 2023-2025 | |
| 76 | Evan Marshall# | 20.1 | 2015-2025 | |
| 76 | Ethan Small# | 20.1 | 2022-2025 | |
| 79 | Hisashi Iwakuma | 19.2 | 2015-2020 | |
| 80 | Danny Duffy | 19.1 | 2015-2023 | |
| 81 | Roger Clemens# | 19.0 | 2019-2025 | |
| 81 | Chad Hammond# | 19.0 | 2023-2025 | |
| 81 | Clayton Kershaw# | 19.0 | 2015-2025 | |
| 84 | Grant Holmes# | 18.2 | 2018-2025 | |
| 84 | Javier Medina# | 18.2 | 2023-2025 | |
| 84 | Julio Teheran# | 18.2 | 2015-2025 | |
| 84 | Julio Urias# | 18.2 | 2018-2025 | |
| 88 | Al Alburquerque# | 18.1 | 2015-2025 | |
| 88 | William Heflin# | 18.1 | 2025-2025 | |
| 88 | Felix Hernandez | 18.1 | 2015-2021 | |
| 88 | Reggie Lawson# | 18.1 | 2020-2025 | |
| 92 | Cole Irvin# | 18.0 | 2020-2025 | |
| 92 | Mike Minor | 18.0 | 2015-2017 | |
| 92 | Huascar Ynoa# | 18.0 | 2023-2025 | |
| 95 | Eric Hankins# | 17.2 | 2020-2025 | |
| 96 | Sean Burnett | 17.1 | 2015-2019 | |
| 96 | Daniel Norris | 17.1 | 2015-2018 | |
| 98 | Cal García# | 17.0 | 2025-2025 | |
| 98 | Phil Green# | 17.0 | 2022-2025 | |
| 98 | David Hernandez | 17.0 | 2015-2023 |
