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| Sunday, November 30th, 2025 |
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| RP Kyle Freeland becomes a free-agent. |
| SP Jose Cisnero becomes a free-agent. |
| RP Anthony Ranaudo becomes a free-agent. |
| RP Cody Martin becomes a free-agent. |
| RP Dario Alvarez becomes a free-agent. |
| RP Nelson Hernandez becomes a free-agent. |
| C Riley Adams becomes a free-agent. |
| C Tyrone Hall becomes a free-agent. |
| SS Kyler Murray becomes a free-agent. |
| RF Zachary Sullivan becomes a free-agent. |
| CF Ryan Boldt becomes a free-agent. |
| LF Keston Hiura becomes a free-agent. |
| RF Brandon Dudley becomes a free-agent. |
| Saturday, November 1st, 2025 |
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| Promoted RP Brett Lilek to Major League Durham. |
| Promoted RP Andrew Cabezas to Major League Durham. |
| Received RP Rafael Montero from Major League Durham. |
| Received LF Lou Schaefer from Major League Durham. |
| Received RP Nick Bruno from Major League Durham. |
| Received RP Geremi Perez from Major League Durham. |
| Thursday, October 9th, 2025 |
|---|
| Promoted RP Rafael Montero to Major League Durham. |
| Promoted RP Nick Bruno to Major League Durham. |
| Promoted RP Geremi Perez to Major League Durham. |
| Received RP Brett Lilek from Major League Durham. |
| Received C Aaron Pilkington from Double A Cary. |
| Received 2B Ismael Macías from Double A Cary. |
| Received RF Griffin Conine from Double A Cary. |
| Demoted CL Angel Nesbitt to Double A Cary. |
| Demoted RP Kieran Lovegrove to Double A Cary. |
| Saturday, October 4th, 2025 |
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| Promoted LF Lou Schaefer to Major League Durham. |
| Received RP Rafael Montero from Major League Durham. |
| Friday, October 3rd, 2025 |
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| RP Bryan Morris retires. |
| SS Nick Ahmed retires. |
| Received RP Brett Lilek from Major League Durham. |
| Received RP Jerad Eickhoff from Major League Durham. |
| Received RP Kieran Lovegrove from Major League Durham. |
| Activated SP Kyle Freeland from the injured list. |
| Promoted SP Jerad Eickhoff to Major League Durham. |
| Promoted RP Brett Lilek to Major League Durham. |
| Received RP Nick Bruno from Major League Durham. |
| Received RP Geremi Perez from Major League Durham. |
