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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rex Brothers RP | 6 | 3 | 2 | 1.66 | 58 | 0 | 54.1 | 31 | 10 | 10 | 4 | 27 | 71 | 1.07 | .169 | .245 | 0.7 |
| Scott Elbert RP | 2 | 0 | 1 | 1.80 | 51 | 0 | 25.0 | 15 | 5 | 5 | 2 | 5 | 25 | 0.80 | .174 | .213 | 0.3 |
| Trevor Rosenthal CL | 8 | 6 | 55 | 1.81 | 79 | 0 | 84.1 | 58 | 17 | 17 | 3 | 34 | 102 | 1.09 | .198 | .291 | 1.6 |
| Robinson Salazar RP | 8 | 5 | 2 | 2.19 | 90 | 0 | 86.1 | 58 | 22 | 21 | 6 | 21 | 121 | 0.92 | .186 | .281 | 2.3 |
| Felix Hernandez SP | 23 | 6 | 0 | 2.22 | 34 | 34 | 259.0 | 201 | 69 | 64 | 11 | 42 | 186 | 0.94 | .214 | .255 | 6.4 |
| Jonathan Broxton RP | 2 | 2 | 2 | 2.68 | 49 | 0 | 53.2 | 38 | 16 | 16 | 1 | 19 | 55 | 1.06 | .194 | .264 | 1.0 |
| Andrew Cashner RP | 2 | 1 | 3 | 2.70 | 27 | 4 | 60.0 | 44 | 19 | 18 | 4 | 15 | 51 | 0.98 | .204 | .248 | 1.1 |
| Brady Aiken SP | 16 | 3 | 0 | 2.88 | 30 | 30 | 187.2 | 156 | 62 | 60 | 17 | 46 | 184 | 1.08 | .224 | .277 | 3.8 |
| Matt Moore SP | 14 | 6 | 0 | 3.50 | 31 | 31 | 198.0 | 156 | 82 | 77 | 20 | 70 | 183 | 1.14 | .214 | .257 | 2.4 |
| Yu Darvish SP | 14 | 10 | 0 | 3.56 | 32 | 32 | 217.2 | 187 | 89 | 86 | 22 | 65 | 239 | 1.16 | .229 | .294 | 4.0 |
| Will Smith RP | 3 | 1 | 2 | 3.76 | 34 | 1 | 64.2 | 62 | 30 | 27 | 7 | 23 | 55 | 1.31 | .254 | .296 | 0.3 |
| Yordano Ventura SP | 13 | 8 | 0 | 4.58 | 30 | 30 | 179.0 | 187 | 96 | 91 | 18 | 60 | 159 | 1.38 | .267 | .321 | 2.2 |
