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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OAVG | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Kensaku Yamaguchi# | .1687 | 2025 | |
| 2 | Eduardo Rodriguez# | .1962 | 2025 | |
| 3 | Chris Sale# | .1987 | 2015 | |
| 4 | William Heflin# | .2016 | 2025 | |
| 5 | Alex Reyes# | .2022 | 2024 | |
| 6 | Jose Fernandez# | .2026 | 2015 | |
| 7 | Jose Fernandez# | .2068 | 2019 | |
| 8 | Chris Sale# | .2071 | 2018 | |
| 9 | Robby Stone# | .2072 | 2024 | |
| 10 | Alex Reyes# | .2074 | 2022 | |
| 11 | Julio Urias# | .2077 | 2025 | |
| 12 | Sonny Gray# | .2088 | 2019 | |
| 13 | Matt Wisler# | .2122 | 2018 | |
| 14 | Matt Wisler# | .2136 | 2025 | |
| 15 | Robby Stone# | .2140 | 2025 | |
| 16 | Jackson Kowar# | .2146 | 2021 | |
| 17 | Jeurys Familia | .2149 | 2022 | |
| 17 | Yordano Ventura# | .2149 | 2025 | |
| 19 | Nate Karns | .2163 | 2020 | |
| 20 | César Valdés# | .2172 | 2024 | |
| 21 | Julio Urias# | .2183 | 2022 | |
| 22 | Carlos Rodon# | .2198 | 2022 | |
| 23 | Adam Conley# | .2199 | 2019 | |
| 24 | Chris Sale# | .2201 | 2020 | |
| 25 | Eduardo Rodriguez# | .2209 | 2022 | |
| 26 | Jacob deGrom | .2210 | 2015 | |
| 27 | Matt Wisler# | .2212 | 2021 | |
| 28 | Kensaku Yamaguchi# | .2213 | 2024 | |
| 29 | Jose Fernandez# | .2215 | 2020 | |
| 30 | Noah Syndergaard# | .2221 | 2016 | |
| 31 | Chris Sale# | .2234 | 2017 | |
| 32 | Taijuan Walker# | .2240 | 2019 | |
| 33 | Nick Pratto# | .2242 | 2022 | |
| 34 | Danny Duffy | .2243 | 2020 | |
| 35 | Matt Wisler# | .2250 | 2020 | |
| 36 | Jose Fernandez# | .2251 | 2018 | |
| 37 | Kolby Allard# | .2254 | 2024 | |
| 38 | Noah Syndergaard# | .2272 | 2020 | |
| 39 | Chris Sale# | .2275 | 2016 | |
| 40 | Jacob deGrom | .2278 | 2020 | |
| 41 | Daniel Norris | .2280 | 2016 | |
| 42 | Alex Reyes# | .2282 | 2023 | |
| 42 | Clayton Kershaw# | .2282 | 2016 | |
| 44 | Noah Syndergaard# | .2287 | 2019 | |
| 44 | Grant Holmes# | .2287 | 2022 | |
| 46 | Max Scherzer | .2289 | 2017 | |
| 47 | Chris Sale# | .2296 | 2021 | |
| 47 | Jake Arrieta | .2296 | 2015 | |
| 49 | Ryan Olson# | .2299 | 2025 | |
| 50 | Alex Reyes# | .2301 | 2025 | |
| 51 | Jacob deGrom | .2304 | 2018 | |
| 52 | Matt Harvey | .2307 | 2017 | |
| 52 | Carlos Rodon# | .2307 | 2020 | |
| 54 | Martin Perez# | .2311 | 2022 | |
| 55 | Julio Teheran# | .2313 | 2018 | |
| 55 | Matt Garza | .2313 | 2016 | |
| 55 | Jerad Eickhoff# | .2313 | 2021 | |
| 55 | Stephen Strasburg | .2313 | 2019 | |
| 59 | Julio Urias# | .2315 | 2024 | |
| 60 | Danny Duffy | .2318 | 2019 | |
| 61 | Jerad Eickhoff# | .2320 | 2020 | |
| 62 | Tong-myeon Kim# | .2323 | 2021 | |
| 62 | Roger Clemens# | .2323 | 2020 | |
| 64 | Carlos Martinez | .2327 | 2016 | |
| 64 | Jim Bartlett# | .2327 | 2025 | |
| 64 | Noah Murdock# | .2327 | 2025 | |
| 67 | Sonny Gray# | .2329 | 2017 | |
| 68 | César Valdés# | .2330 | 2025 | |
| 69 | Masahiro Tanaka | .2333 | 2017 | |
| 70 | Noah Syndergaard# | .2334 | 2017 | |
| 71 | Jeurys Familia | .2336 | 2023 | |
| 72 | Roger Clemens# | .2338 | 2021 | |
| 73 | Charles King# | .2340 | 2025 | |
| 74 | Marcus Stroman# | .2341 | 2022 | |
| 74 | Trevor Hillhouse# | .2341 | 2023 | |
| 76 | Jameson Taillon# | .2342 | 2018 | |
| 77 | Grant Holmes# | .2343 | 2023 | |
| 78 | Sonny Gray# | .2354 | 2020 | |
| 78 | Jackson Kowar# | .2354 | 2020 | |
| 78 | Max Scherzer | .2354 | 2016 | |
| 81 | Noah Syndergaard# | .2355 | 2025 | |
| 81 | Chad Hammond# | .2355 | 2025 | |
| 83 | Ricardo Sanchez# | .2356 | 2023 | |
| 84 | Jefry Rodriguez# | .2359 | 2021 | |
| 84 | Carlos Rodon# | .2359 | 2024 | |
| 86 | Shelby Miller# | .2360 | 2021 | |
| 86 | Chris Beck# | .2360 | 2019 | |
| 88 | Sandy Koufax# | .2361 | 2021 | |
| 88 | Alex Wood# | .2361 | 2019 | |
| 90 | Max Scherzer | .2363 | 2019 | |
| 91 | Nick Kingham# | .2364 | 2021 | |
| 91 | Marcus Stroman# | .2364 | 2016 | |
| 93 | Marcus Stroman# | .2368 | 2015 | |
| 93 | Matt Wisler# | .2368 | 2017 | |
| 95 | Chris Sale# | .2369 | 2022 | |
| 96 | Garrett Richards | .2370 | 2015 | |
| 97 | Grant Holmes# | .2372 | 2020 | |
| 97 | Ricardo Sanchez# | .2372 | 2025 | |
| 99 | Damien Magnifico# | .2373 | 2022 | |
| 100 | Zack Greinke | .2375 | 2016 |
