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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Ken Giles# | 13.1 | 2015-2025 | |
| 2 | Kenley Jansen | 12.7 | 2015-2023 | |
| 3 | Aroldis Chapman | 12.6 | 2015-2025 | |
| 4 | Cody Allen# | 12.4 | 2015-2025 | |
| 5 | Kensaku Yamaguchi# | 12.3 | 2023-2025 | |
| 6 | Craig Kimbrel | 12.1 | 2015-2022 | |
| 6 | Jacob Lindgren# | 12.1 | 2016-2025 | |
| 8 | Shae Simmons# | 12.0 | 2015-2025 | |
| 9 | Al Alburquerque# | 11.9 | 2015-2025 | |
| 10 | Sam Tuivailala# | 11.7 | 2016-2025 | |
| 11 | Jose Valdez# | 11.6 | 2015-2025 | |
| 11 | Paco Rodriguez# | 11.6 | 2015-2025 | |
| 13 | Brad Boxberger | 11.1 | 2015-2021 | |
| 14 | Kyle Crockett# | 11.0 | 2015-2025 | |
| 15 | Wade Davis | 10.7 | 2015-2023 | |
| 16 | Jordan Walden# | 10.6 | 2015-2025 | |
| 17 | Steven Okert# | 10.4 | 2018-2025 | |
| 18 | Carter Capps# | 10.3 | 2015-2025 | |
| 18 | Jesus Zambrano# | 10.3 | 2023-2025 | |
| 20 | Kelvin Herrera | 10.2 | 2015-2025 | |
| 20 | Alex Claudio# | 10.2 | 2015-2025 | |
| 22 | C.J. Edwards | 10.1 | 2016-2024 | |
| 23 | Mike Morin# | 9.8 | 2016-2025 | |
| 24 | Jackson Kowar# | 9.6 | 2019-2025 | |
| 25 | Alex Reyes# | 9.5 | 2020-2025 | |
| 25 | Evan Scribner | 9.5 | 2015-2021 | |
| 27 | Huston Street | 9.4 | 2015-2023 | |
| 27 | Dan Reynolds# | 9.4 | 2016-2025 | |
| 29 | Anthony Molina# | 9.3 | 2022-2025 | |
| 29 | Julio Urias# | 9.3 | 2018-2025 | |
| 31 | Hunter Harvey# | 9.2 | 2018-2025 | |
| 31 | Phil Klein# | 9.2 | 2018-2025 | |
| 31 | Damien Magnifico# | 9.2 | 2016-2025 | |
| 34 | Trevor Rosenthal# | 9.1 | 2015-2025 | |
| 35 | Adam Conley# | 9.0 | 2018-2024 | |
| 36 | Sandy Koufax# | 8.9 | 1955-2025 | |
| 36 | Jeurys Familia | 8.9 | 2015-2025 | |
| 36 | Evan Marshall# | 8.9 | 2015-2025 | |
| 36 | Robby Stone# | 8.9 | 2020-2025 | |
| 40 | Roman Mendez | 8.8 | 2015-2025 | |
| 40 | Andrew McKirahan# | 8.8 | 2018-2025 | |
| 40 | Tyler Glasnow# | 8.8 | 2017-2025 | |
| 40 | Drew Pomeranz# | 8.8 | 2015-2025 | |
| 40 | Richard Rodriguez# | 8.8 | 2016-2025 | |
| 45 | Matt Ramsey# | 8.7 | 2016-2025 | |
| 45 | Hogan Harris | 8.7 | 2022-2025 | |
| 45 | Dellin Betances | 8.7 | 2015-2024 | |
| 48 | Roger Clemens# | 8.6 | 2019-2025 | |
| 48 | Nate Karns | 8.6 | 2015-2023 | |
| 50 | Trevor Hillhouse# | 8.5 | 2023-2025 | |
| 50 | Ben Jordan# | 8.5 | 2021-2025 | |
| 52 | Henry Owens | 8.4 | 2016-2022 | |
| 52 | Carlos Martinez | 8.4 | 2015-2023 | |
| 52 | Ricardo Sanchez# | 8.4 | 2021-2025 | |
| 52 | Justin De Fratus# | 8.4 | 2015-2024 | |
| 52 | Drew Storen# | 8.4 | 2015-2025 | |
| 52 | Julio Teheran# | 8.4 | 2015-2025 | |
| 52 | Trevor Bauer | 8.4 | 2015-2020 | |
| 52 | Jose Fernandez# | 8.4 | 2015-2025 | |
| 60 | Clayton Kershaw# | 8.3 | 2015-2025 | |
| 60 | Stephen Strasburg | 8.3 | 2015-2021 | |
| 60 | Toby Kelly# | 8.3 | 2022-2025 | |
| 63 | Shelby Miller# | 8.2 | 2015-2025 | |
| 63 | Ryan Olson# | 8.2 | 2022-2025 | |
| 63 | Nick Sprengel# | 8.2 | 2020-2025 | |
| 63 | Carlos Rodon# | 8.2 | 2018-2025 | |
| 63 | Marcos Molina# | 8.2 | 2018-2025 | |
| 68 | Kolby Allard# | 8.1 | 2020-2025 | |
| 68 | Yu Darvish | 8.1 | 2015-2019 | |
| 70 | Stephen Keller# | 8.0 | 2021-2025 | |
| 70 | Noah Syndergaard# | 8.0 | 2015-2025 | |
| 70 | Josh Staumont# | 8.0 | 2020-2025 | |
| 70 | Reggie Lawson# | 8.0 | 2020-2025 | |
| 70 | Cody Poteet# | 8.0 | 2019-2025 | |
| 70 | Chris Sale# | 8.0 | 2015-2025 | |
| 76 | Zach Britton# | 7.9 | 2015-2025 | |
| 76 | Matt Wisler# | 7.9 | 2016-2025 | |
| 76 | Jose E. De Leon# | 7.9 | 2017-2025 | |
| 76 | Grant Holmes# | 7.9 | 2018-2025 | |
| 80 | Jerad Eickhoff# | 7.8 | 2016-2025 | |
| 80 | Yordano Ventura# | 7.8 | 2016-2025 | |
| 80 | Chris Archer | 7.8 | 2015-2018 | |
| 83 | Madison Bumgarner# | 7.7 | 2015-2022 | |
| 83 | Tyler Keysor# | 7.7 | 2021-2025 | |
| 83 | Chandler Day# | 7.7 | 2021-2025 | |
| 86 | Michael Wacha# | 7.6 | 2015-2025 | |
| 86 | Tony Cingrani | 7.6 | 2015-2019 | |
| 86 | Cole Irvin# | 7.6 | 2020-2025 | |
| 86 | Max Scherzer | 7.6 | 2015-2021 | |
| 90 | Juan Hillman# | 7.5 | 2020-2025 | |
| 90 | Rafael Montero# | 7.5 | 2016-2024 | |
| 90 | Jeff Samardzija | 7.5 | 2015-2021 | |
| 90 | Sonny Gray# | 7.5 | 2015-2025 | |
| 94 | Ian Kennedy | 7.4 | 2015-2022 | |
| 94 | Nick Pivetta# | 7.4 | 2022-2025 | |
| 94 | Tyson Ross | 7.4 | 2015-2024 | |
| 94 | Jacob deGrom | 7.4 | 2015-2022 | |
| 98 | Gerrit Cole | 7.3 | 2015-2025 | |
| 98 | Matt Harvey | 7.3 | 2015-2023 | |
| 98 | Masahiro Tanaka | 7.3 | 2015-2024 |
